Dr. Kotb Abdelmohsen received his Ph.D. in Biochemistry from Heinrich Heine University in Düsseldorf, Germany. His postdoctoral work at the NIH’s National Institute on Aging (NIA) focused on post-transcriptional gene regulation. His research explores the roles of RNA-binding proteins and noncoding RNAs in gene expression, crucial for understanding stress responses, senescence, and aging.
As a Senior Associate Scientist at NIA, Dr. Abdelmohsen investigates RNA modifications, stability, and translation, focusing on the interaction between RNA-binding proteins and RNA sequences. His research spans both coding and noncoding RNAs, exploring their impact on cell growth, aging, and senescence. Further, Dr. Abdelmohsen is investigating extracellular vesicles and particles from various organs and cells including the human trophoblast stem cells to advance our understanding of cellular aging and senescence. Leveraging the unique features of these nanoparticles, his work offers insights into cellular senescence, aging and disease, aiming to develop anti-aging and senotherapeutic strategies.